increased tumor growth/size_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>,Tg(MMTV-vHaras)SH1Led/0

http://metadb.riken.jp/0003721I129S4SvJaeSorC57BL6JCD1Cdkn1btm1MlfCdkn1btm1MlfTgMMTVvHarasSH1Led0TgMMTVvHarasSH1LedCdkn1btm1Mlf

increased tumor growth/size_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>,Tg(MMTV-vHaras)SH1Led/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565
• transgene insertion SH1, Philip Leder
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653621

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>,Tg(MMTV-vHaras)SH1Led/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-vHaras)SH1Led|Cdkn1b<tm1Mlf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6J * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003721

文献

http://purl.org/net/cito/citesAsAuthority

• Rosalind J. Jackson, et.al., Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models., Oncogene, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/12466968