increased tumor growth/size_Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0003721I129S7SvEvBrd129X1SvJC57BL6NIHOlaHsdCdkn2atm1CjsCdkn2atm1CjsTrp53tm1BrdTrp53tm1BrdCdkn2atm1CjsTrp53tm1Brd

increased tumor growth/size_Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Cjs>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * NIH/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003721

文献

http://purl.org/net/cito/citesAsAuthority

• Karen S. Kelly-Spratt, et.al., p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways., PLoS biology, 2004, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/15314658