abnormal retinal photoreceptor layer morphology_Crb1<tm1Wij>/Crb1<tm2Wij>

http://metadb.riken.jp/0003728I129P2OlaHsdC57BL6Crb1tm1WijCrb1tm2WijCrb1tm2WijCrb1tm1Wij

abnormal retinal photoreceptor layer morphology_Crb1<tm1Wij>/Crb1<tm2Wij>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• crumbs family member 1, photoreceptor morphogenesis associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136343

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crb1<tm1Wij>/Crb1<tm2Wij>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Crb1<tm2Wij>|Crb1<tm1Wij>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retinal photoreceptor layer morphology
  http://purl.obolibrary.org/obo/MP_0003728

文献

http://purl.org/net/cito/citesAsAuthority

• Serge A. van de Pavert, et.al., A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17234588