oral leukoplakia_Terf1<tm1.1Blas>/Terf1<tm1.1Blas>,Tg(KRT5-cre)1Tak/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0003751I129C3HC57BL6SJLTerf1tm11BlasTerf1tm11BlasTgKRT5cre1Tak0Trp53tm1TyjTrp53tm1TyjTerf1tm11BlasTgKRT5cre1TakTrp53tm1Tyj

oral leukoplakia_Terf1<tm1.1Blas>/Terf1<tm1.1Blas>,Tg(KRT5-cre)1Tak/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926776
• telomeric repeat binding factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109634

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Terf1<tm1.1Blas>/Terf1<tm1.1Blas>,Tg(KRT5-cre)1Tak/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Terf1<tm1.1Blas>|Tg(KRT5-cre)1Tak|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C3H * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• oral leukoplakia
  http://purl.obolibrary.org/obo/MP_0003751

文献

http://purl.org/net/cito/citesAsAuthority

• Paula. Martínez, et.al., Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice., Genes & development, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/19679647