abnormal imprinting_Rr27<tm1.1Msb>/Rr27<+>

http://metadb.riken.jp/0003787I129P2OlaHsdC57BL6JRr27tm11MsbRr27Rr27Rr27tm11Msb

abnormal imprinting_Rr27<tm1.1Msb>/Rr27<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• regulatory region 27
  http://metadb.riken.jp/db/mgi_rdf/MGI:5489785

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rr27<tm1.1Msb>/Rr27<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rr27<+>|Rr27<tm1.1Msb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal imprinting
  http://purl.obolibrary.org/obo/MP_0003787

文献

http://purl.org/net/cito/citesAsAuthority

• Joanne L. Thorvaldsen, et.al., Analysis of sequence upstream of the endogenous H19 gene reveals elements both essential and dispensable for imprinting., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/11909940
• Joanne L. Thorvaldsen, et.al., Developmental profile of H19 differentially methylated domain (DMD) deletion alleles reveals multiple roles of the DMD in regulating allelic expression and DNA methylation at the imprinted H19/Igf2 locus., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16449639
• J L. Thorvaldsen, et.al., Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2., Genes & development, 1998, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/9851976