impaired macrophage chemotaxis_Apoe<tm1Bres>/Apoe<tm1Bres>,Cx3cr1<tm1Ifc>/Cx3cr1<tm1Ifc>

http://metadb.riken.jp/0003799I129P2OlaHsd129S4SvJaeC57BL6Apoetm1BresApoetm1BresCx3cr1tm1IfcCx3cr1tm1IfcCx3cr1tm1IfcApoetm1Bres

impaired macrophage chemotaxis_Apoe<tm1Bres>/Apoe<tm1Bres>,Cx3cr1<tm1Ifc>/Cx3cr1<tm1Ifc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-X3-C motif) receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333815
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Bres>/Apoe<tm1Bres>,Cx3cr1<tm1Ifc>/Cx3cr1<tm1Ifc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cx3cr1<tm1Ifc>|Apoe<tm1Bres>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired macrophage chemotaxis
  http://purl.obolibrary.org/obo/MP_0003799

文献

http://purl.org/net/cito/citesAsAuthority

• Philippe. Lesnik, et.al., Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis., The Journal of clinical investigation, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/12569158