impaired macrophage chemotaxis_Apoe<tm1Unc>/Apoe<tm1Unc>,Ccr2<tm1Ifc>/Ccr2<tm1Ifc>

http://metadb.riken.jp/0003799I129P2OlaHsd129S4SvJaeC57BL6Apoetm1UncApoetm1UncCcr2tm1IfcCcr2tm1IfcApoetm1UncCcr2tm1Ifc

impaired macrophage chemotaxis_Apoe<tm1Unc>/Apoe<tm1Unc>,Ccr2<tm1Ifc>/Ccr2<tm1Ifc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-C motif) receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:106185
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Ccr2<tm1Ifc>/Ccr2<tm1Ifc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apoe<tm1Unc>|Ccr2<tm1Ifc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired macrophage chemotaxis
  http://purl.obolibrary.org/obo/MP_0003799

文献

http://purl.org/net/cito/citesAsAuthority

• L. Boring, et.al., Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis., Nature, 1998, 394
  http://rdf.ncbi.nlm.nih.gov/pubmed/9732872