increased left ventricle diastolic pressure_Gab1<tm1Nmoc>/Gab1<tm1Nmoc>,Gab2<tm1Thir>/Gab2<tm1Thir>,Tg(Myh6-cre)2182Mds/?

http://metadb.riken.jp/0003819I129S1Sv129X1SvJC57BL6JFVBNGab1tm1NmocGab1tm1NmocGab2tm1ThirGab2tm1ThirTgMyh6cre2182MdsTgMyh6cre2182MdsGab1tm1NmocGab2tm1Thir

increased left ventricle diastolic pressure_Gab1<tm1Nmoc>/Gab1<tm1Nmoc>,Gab2<tm1Thir>/Gab2<tm1Thir>,Tg(Myh6-cre)2182Mds/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• growth factor receptor bound protein 2-associated protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333854
• growth factor receptor bound protein 2-associated protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:108088

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gab1<tm1Nmoc>/Gab1<tm1Nmoc>,Gab2<tm1Thir>/Gab2<tm1Thir>,Tg(Myh6-cre)2182Mds/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-cre)2182Mds|Gab1<tm1Nmoc>|Gab2<tm1Thir>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased left ventricle diastolic pressure
  http://purl.obolibrary.org/obo/MP_0003819

文献

http://purl.org/net/cito/citesAsAuthority

• Yoshikazu. Nakaoka, et.al., Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17571162