increased left ventricle diastolic pressure_Tg(Myh6-ADRBK1)27Wjk/0

http://metadb.riken.jp/0003819IC57BL6SJLTgMyh6ADRBK127Wjk0TgMyh6ADRBK127Wjk

increased left ventricle diastolic pressure_Tg(Myh6-ADRBK1)27Wjk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 27, Walter Koch
  http://metadb.riken.jp/db/mgi_rdf/MGI:3037311

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Myh6-ADRBK1)27Wjk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-ADRBK1)27Wjk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased left ventricle diastolic pressure
  http://purl.obolibrary.org/obo/MP_0003819

文献

http://purl.org/net/cito/citesAsAuthority

• S A. Akhter, et.al., In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function., Circulation, 1999, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/10441103
• W J. Koch, et.al., Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor., Science (New York, N.Y.), 1995, 268
  http://rdf.ncbi.nlm.nih.gov/pubmed/7761854