impaired febrile response_Ptger3<tm1Csml>/Ptger3<tm1Csml>,Tg(Nes-cre)1Kln/?

http://metadb.riken.jp/0003829I129S4SvJaeC57BL6SJLPtger3tm1CsmlPtger3tm1CsmlTgNescre1KlnTgNescre1KlnPtger3tm1Csml

impaired febrile response_Ptger3<tm1Csml>/Ptger3<tm1Csml>,Tg(Nes-cre)1Kln/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• prostaglandin E receptor 3 (subtype EP3)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97795

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptger3<tm1Csml>/Ptger3<tm1Csml>,Tg(Nes-cre)1Kln/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Ptger3<tm1Csml>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired febrile response
  http://purl.obolibrary.org/obo/MP_0003829

文献

http://purl.org/net/cito/citesAsAuthority

• Michael. Lazarus, et.al., EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses., Nature neuroscience, 2007, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/17676060