decreased macrophage cell number_Ldlr<tm1Her>/Ldlr<tm1Her>,Mapkapk2<tm1Mgl>/Mapkapk2<tm1Mgl>

http://metadb.riken.jp/0003884I129P2OlaHsd129S7SvEvBrdC57BL6Ldlrtm1HerLdlrtm1HerMapkapk2tm1MglMapkapk2tm1MglLdlrtm1HerMapkapk2tm1Mgl

decreased macrophage cell number_Ldlr<tm1Her>/Ldlr<tm1Her>,Mapkapk2<tm1Mgl>/Mapkapk2<tm1Mgl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MAP kinase-activated protein kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109298
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ldlr<tm1Her>/Ldlr<tm1Her>,Mapkapk2<tm1Mgl>/Mapkapk2<tm1Mgl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<tm1Her>|Mapkapk2<tm1Mgl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased macrophage cell number
  http://purl.obolibrary.org/obo/MP_0003884

文献

http://purl.org/net/cito/citesAsAuthority

• Kumaravelu. Jagavelu, et.al., Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice., Circulation research, 2007, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/17885219