decreased macrophage cell number_Hmox1<tm1Poss>/Hmox1<tm1Poss>,Spic<tm2Kmm>/Spic<tm2Kmm>

http://metadb.riken.jp/0003884I129S2SvPas129S6SvEvTacC57BL6FVBNHmox1tm1PossHmox1tm1PossSpictm2KmmSpictm2KmmHmox1tm1PossSpictm2Kmm

decreased macrophage cell number_Hmox1<tm1Poss>/Hmox1<tm1Poss>,Spic<tm2Kmm>/Spic<tm2Kmm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Spi-C transcription factor (Spi-1/PU.1 related)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341168
• heme oxygenase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96163

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmox1<tm1Poss>/Hmox1<tm1Poss>,Spic<tm2Kmm>/Spic<tm2Kmm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hmox1<tm1Poss>|Spic<tm2Kmm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased macrophage cell number
  http://purl.obolibrary.org/obo/MP_0003884

文献

http://purl.org/net/cito/citesAsAuthority

• Malay. Haldar, et.al., Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages., Cell, 2014, 156
  http://rdf.ncbi.nlm.nih.gov/pubmed/24630724