increased hepatocyte apoptosis_Rela<tm1Bal>/Rela<tm1Bal>,Tg(SERPINA1-BCL2)1Pva/0

http://metadb.riken.jp/0003887I129S4SvJaeC57BL6DBA2Relatm1BalRelatm1BalTgSERPINA1BCL21Pva0Relatm1BalTgSERPINA1BCL21Pva

increased hepatocyte apoptosis_Rela<tm1Bal>/Rela<tm1Bal>,Tg(SERPINA1-BCL2)1Pva/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Pierre Vassalli
  http://metadb.riken.jp/db/mgi_rdf/MGI:3799176
• v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  http://metadb.riken.jp/db/mgi_rdf/MGI:103290

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rela<tm1Bal>/Rela<tm1Bal>,Tg(SERPINA1-BCL2)1Pva/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rela<tm1Bal>|Tg(SERPINA1-BCL2)1Pva

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003887

文献

http://purl.org/net/cito/citesAsAuthority

• R. Gugasyan, et.al., Bcl-2 transgene expression fails to prevent fatal hepatocyte apoptosis induced by endogenous TNFalpha in mice lacking RelA., Cell death and differentiation, 2006, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/16485035