increased hepatocyte apoptosis_Sod2<tm1Cje>/Sod2<+>

http://metadb.riken.jp/0003887IC57BL6JCD1Sod2tm1CjeSod2Sod2tm1CjeSod2

increased hepatocyte apoptosis_Sod2<tm1Cje>/Sod2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• superoxide dismutase 2, mitochondrial
  http://metadb.riken.jp/db/mgi_rdf/MGI:98352

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sod2<tm1Cje>/Sod2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sod2<tm1Cje>|Sod2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003887

文献

http://purl.org/net/cito/citesAsAuthority

• J E. Kokoszka, et.al., Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11226230