increased hepatocyte proliferation_Rara<tm3Ipc>/Rara<tm3Ipc>,Tg(Alb-cre)21Mgn/?,Trim24<tm1Los>/Trim24<tm1Los>

http://metadb.riken.jp/0003893I129SvC57BL6DBASJLRaratm3IpcRaratm3IpcTgAlbcre21MgnTrim24tm1LosTrim24tm1LosRaratm3IpcTgAlbcre21MgnTrim24tm1Los

increased hepatocyte proliferation_Rara<tm3Ipc>/Rara<tm3Ipc>,Tg(Alb-cre)21Mgn/?,Trim24<tm1Los>/Trim24<tm1Los>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tripartite motif-containing 24
  http://metadb.riken.jp/db/mgi_rdf/MGI:109275
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• retinoic acid receptor, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:97856

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rara<tm3Ipc>/Rara<tm3Ipc>,Tg(Alb-cre)21Mgn/?,Trim24<tm1Los>/Trim24<tm1Los>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rara<tm3Ipc>|Tg(Alb-cre)21Mgn|Trim24<tm1Los>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * DBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte proliferation
  http://purl.obolibrary.org/obo/MP_0003893

文献

http://purl.org/net/cito/citesAsAuthority

• Konstantin. Khetchoumian, et.al., Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha., Nature genetics, 2007, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/18026104