abnormal heart left ventricle morphology_Gt(ROSA)26Sor<tm4(HIF2A*)Kael>/Gt(ROSA)26Sor<+>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0003921I129S6SvEvTacFVBNGtROSA26Sortm4HIF2AKaelGtROSA26SorTgMyh6cre2182Mds0GtROSA26SorGtROSA26Sortm4HIF2AKaelTgMyh6cre2182Mds

abnormal heart left ventricle morphology_Gt(ROSA)26Sor<tm4(HIF2A*)Kael>/Gt(ROSA)26Sor<+>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm4(HIF2A*)Kael>/Gt(ROSA)26Sor<+>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm4(HIF2A*)Kael>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal heart left ventricle morphology
  http://purl.obolibrary.org/obo/MP_0003921

文献

http://purl.org/net/cito/citesAsAuthority

• Javid. Moslehi, et.al., Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy., Circulation, 2010, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/20733101