abnormal T cell subpopulation ratio_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0003944I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm

abnormal T cell subpopulation ratio_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261423
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp8<tm1Raz>|Tg(Lck-cre)548Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell subpopulation ratio
  http://purl.obolibrary.org/obo/MP_0003944

文献

http://purl.org/net/cito/citesAsAuthority

• Leonardo. Salmena, et.al., Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder., The Journal of experimental medicine, 2005, 202
  http://rdf.ncbi.nlm.nih.gov/pubmed/16157684
• Leonardo. Salmena, et.al., Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity., Genes & development, 2003, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12654726