decreased circulating phospholipid level_Abca1<tm2Jp>/Abca1<tm2Jp>,Tg(APOA1)427Bres/?

http://metadb.riken.jp/0003981I129X1SvJC57BL6JCBAJAbca1tm2JpAbca1tm2JpTgAPOA1427BresTgAPOA1427BresAbca1tm2Jp

decreased circulating phospholipid level_Abca1<tm2Jp>/Abca1<tm2Jp>,Tg(APOA1)427Bres/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATP-binding cassette, sub-family A (ABC1), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99607
• transgene insertion 427, Jan L Breslow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3614552

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abca1<tm2Jp>/Abca1<tm2Jp>,Tg(APOA1)427Bres/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APOA1)427Bres|Abca1<tm2Jp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating phospholipid level
  http://purl.obolibrary.org/obo/MP_0003981

文献

http://purl.org/net/cito/citesAsAuthority

• Ji-Young. Lee, et.al., HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney., Journal of lipid research, 2005, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/16024913