increased cholesterol level_Npc1<m1N>/Npc1<m1N>

http://metadb.riken.jp/0003982IBALBcNpc1m1NNpc1m1NNpc1m1N

increased cholesterol level_Npc1<m1N>/Npc1<m1N>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Niemann-Pick type C1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097712

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Npc1<m1N>/Npc1<m1N>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Npc1<m1N>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cholesterol level
  http://purl.obolibrary.org/obo/MP_0003982

文献

http://purl.org/net/cito/citesAsAuthority

• Joyce J. Repa, et.al., Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/18160655
• C. Xie, et.al., Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased., Journal of neuropathology and experimental neurology, 2000, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/11138930
• Blair R. Roszell, et.al., Pulmonary abnormalities in animal models due to Niemann-Pick type C1 (NPC1) or C2 (NPC2) disease., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/23843985