embryonic growth retardation_Lrp5<tm1Kry>/Lrp5<tm1Kry>,Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>/Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>,Tg(Sox2-cre)1Amc/?

http://metadb.riken.jp/0003984I129C57BL6CBALrp5tm1KryLrp5tm1KryIgs1tm2CAGBgeoNdpEGFPNatIgs1tm2CAGBgeoNdpEGFPNatTgSox2cre1AmcIgs1tm2CAGBgeoNdpEGFPNatTgSox2cre1AmcLrp5tm1Kry

embryonic growth retardation_Lrp5<tm1Kry>/Lrp5<tm1Kry>,Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>/Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>,Tg(Sox2-cre)1Amc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor-related protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1278315
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537
• intergenic site 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319510

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrp5<tm1Kry>/Lrp5<tm1Kry>,Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>/Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>,Tg(Sox2-cre)1Amc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>|Tg(Sox2-cre)1Amc|Lrp5<tm1Kry>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• embryonic growth retardation
  http://purl.obolibrary.org/obo/MP_0003984

文献

http://purl.org/net/cito/citesAsAuthority

• Xin. Ye, et.al., Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization., Cell, 2009, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/19837032