decreased thermal nociceptive threshold_Ppp2r5d<tm1Vjan>/Ppp2r5d<tm1Vjan>,Tg(Thy1-MAPT)5Vln/0

http://metadb.riken.jp/0003998I129P2OlaHsdC57BL6FVBNPpp2r5dtm1VjanPpp2r5dtm1VjanTgThy1MAPT5Vln0TgThy1MAPT5VlnPpp2r5dtm1Vjan

decreased thermal nociceptive threshold_Ppp2r5d<tm1Vjan>/Ppp2r5d<tm1Vjan>,Tg(Thy1-MAPT)5Vln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein phosphatase 2, regulatory subunit B', delta
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388481
• transgene insertion 5, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3720112

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ppp2r5d<tm1Vjan>/Ppp2r5d<tm1Vjan>,Tg(Thy1-MAPT)5Vln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-MAPT)5Vln|Ppp2r5d<tm1Vjan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thermal nociceptive threshold
  http://purl.obolibrary.org/obo/MP_0003998

文献

http://purl.org/net/cito/citesAsAuthority

• Justin V. Louis, et.al., Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21482799