decreased hepatocyte proliferation_Itih4<tm1Mish>/Itih4<tm1Mish>,Sptbn1<tm1Mish>/Sptbn1<+>

http://metadb.riken.jp/0004001I129S6SvEvTacC57BL6NIHBlackSwissItih4tm1MishItih4tm1MishSptbn1tm1MishSptbn1Sptbn1tm1MishSptbn1Itih4tm1Mish

decreased hepatocyte proliferation_Itih4<tm1Mish>/Itih4<tm1Mish>,Sptbn1<tm1Mish>/Sptbn1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• inter alpha-trypsin inhibitor, heavy chain 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:109536
• spectrin beta, non-erythrocytic 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98388

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itih4<tm1Mish>/Itih4<tm1Mish>,Sptbn1<tm1Mish>/Sptbn1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sptbn1<tm1Mish>|Sptbn1<+>|Itih4<tm1Mish>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hepatocyte proliferation
  http://purl.obolibrary.org/obo/MP_0004001

文献

http://purl.org/net/cito/citesAsAuthority

• Yi. Tang, et.al., Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18263735