abnormal GABA-mediated receptor currents_Ube3a<tm1.1Bdph>/Ube3a<+>,Tg(Th-cre)1Tmd/0

http://metadb.riken.jp/0004008B6CgUbe3atm11BdphTgThcre1TmdUbe3atm11BdphUbe3aTgThcre1Tmd0Ube3aTgThcre1TmdUbe3atm11Bdph

abnormal GABA-mediated receptor currents_Ube3a<tm1.1Bdph>/Ube3a<+>,Tg(Th-cre)1Tmd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Ted M Dawson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584377
• ubiquitin protein ligase E3A
  http://metadb.riken.jp/db/mgi_rdf/MGI:105098

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ube3a<tm1.1Bdph>/Ube3a<+>,Tg(Th-cre)1Tmd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ube3a<+>|Tg(Th-cre)1Tmd|Ube3a<tm1.1Bdph>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Ube3a<tm1.1Bdph> Tg(Th-cre)1Tmd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal GABA-mediated receptor currents
  http://purl.obolibrary.org/obo/MP_0004008

文献

http://purl.org/net/cito/citesAsAuthority

• Janet. Berrios, et.al., Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation., Nature communications, 2016, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/26869263