spontaneous chromosome breakage_Aicda<tm1(cre)Mnz>/Aicda<+>,Igh<tm3Mnz>/Igh<+>,Myc<tm39Mnz>/Myc<+>

http://metadb.riken.jp/0004029I129P2OlaHsdC57BL6Aicdatm1creMnzAicdaIghtm3MnzIghMyctm39MnzMycIghMyctm39MnzAicdaMycIghtm3MnzAicdatm1creMnz

spontaneous chromosome breakage_Aicda<tm1(cre)Mnz>/Aicda<+>,Igh<tm3Mnz>/Igh<+>,Myc<tm39Mnz>/Myc<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279
• myelocytomatosis oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97250
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1(cre)Mnz>/Aicda<+>,Igh<tm3Mnz>/Igh<+>,Myc<tm39Mnz>/Myc<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<+>|Myc<tm39Mnz>|Aicda<+>|Myc<+>|Igh<tm3Mnz>|Aicda<tm1(cre)Mnz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• spontaneous chromosome breakage
  http://purl.obolibrary.org/obo/MP_0004029

文献

http://purl.org/net/cito/citesAsAuthority

• Davide F. Robbiani, et.al., AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations., Cell, 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/19070574