induced chromosome breakage_Aicda<tm1Hon>/Aicda<tm1Hon>,Igh<tm3Mnz>/Igh<+>,Myc<tm37Mnz>/Myc<+>

http://metadb.riken.jp/0004030IC57BL6CBAAicdatm1HonAicdatm1HonIghtm3MnzIghMyctm37MnzMycIghtm3MnzMycIghAicdatm1HonMyctm37Mnz

induced chromosome breakage_Aicda<tm1Hon>/Aicda<tm1Hon>,Igh<tm3Mnz>/Igh<+>,Myc<tm37Mnz>/Myc<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442
• myelocytomatosis oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97250

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1Hon>/Aicda<tm1Hon>,Igh<tm3Mnz>/Igh<+>,Myc<tm37Mnz>/Myc<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm3Mnz>|Myc<+>|Igh<+>|Aicda<tm1Hon>|Myc<tm37Mnz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• induced chromosome breakage
  http://purl.obolibrary.org/obo/MP_0004030

文献

http://purl.org/net/cito/citesAsAuthority

• Davide F. Robbiani, et.al., AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations., Cell, 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/19070574