insulitis_H2<g7>/H2<g7>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcraBDC12-4.1)10Jos/0,Tg(TcrbBDC12-4.1)82Gse/0

http://metadb.riken.jp/0004031I129S7SvEvBrdC57BL6FVBNODH2g7H2g7Rag1tm1MomRag1tm1MomTgTcraBDC124110Jos0TgTcrbBDC124182Gse0TgTcrbBDC124182GseRag1tm1MomTgTcraBDC124110JosH2g7

insulitis_H2<g7>/H2<g7>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcraBDC12-4.1)10Jos/0,Tg(TcrbBDC12-4.1)82Gse/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histocompatibility-2, MHC
  http://metadb.riken.jp/db/mgi_rdf/MGI:95894
• transgene insertion 82, George Eisenbarth
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687033
• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• transgene insertion 10, Joslin Diabetes Center
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687035

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2<g7>/H2<g7>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcraBDC12-4.1)10Jos/0,Tg(TcrbBDC12-4.1)82Gse/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcrbBDC12-4.1)82Gse|Rag1<tm1Mom>|Tg(TcraBDC12-4.1)10Jos|H2<g7>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulitis
  http://purl.obolibrary.org/obo/MP_0004031

文献

http://purl.org/net/cito/citesAsAuthority

• Jean M. Jasinski, et.al., Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout., Diabetes, 2006, 55
  http://rdf.ncbi.nlm.nih.gov/pubmed/16804066