insulitis_Tg(Ins1-Cd80)378Psoh/0,Tg(Ins2-GP)#Psoh/0,Tg(TcrLCMV)327Sdz/0

http://metadb.riken.jp/0004031IC57BL6DBA2FVBNTgIns1Cd80378Psoh0TgIns2GPPsoh0TgTcrLCMV327Sdz0TgIns2GPPsohTgIns1Cd80378PsohTgTcrLCMV327Sdz

insulitis_Tg(Ins1-Cd80)378Psoh/0,Tg(Ins2-GP)#Psoh/0,Tg(TcrLCMV)327Sdz/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 327, Birgit Ledermann
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665109
• transgene insertion, Pamela Ohashi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5568708
• transgene insertion 378, Pamela Ohashi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5569012

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Ins1-Cd80)378Psoh/0,Tg(Ins2-GP)#Psoh/0,Tg(TcrLCMV)327Sdz/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-GP)#Psoh|Tg(Ins1-Cd80)378Psoh|Tg(TcrLCMV)327Sdz

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulitis
  http://purl.obolibrary.org/obo/MP_0004031

文献

http://purl.org/net/cito/citesAsAuthority

• D M. Harlan, et.al., Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/7512724