increased acute promyelocytic leukemia incidence_Ctsg<tm2.1(PML/RARA)Ley>/Ctsg<+>

http://metadb.riken.jp/0004049I129129X1SvJC57BL6Ctsgtm21PMLRARALeyCtsgCtsgCtsgtm21PMLRARALey

increased acute promyelocytic leukemia incidence_Ctsg<tm2.1(PML/RARA)Ley>/Ctsg<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cathepsin G
  http://metadb.riken.jp/db/mgi_rdf/MGI:88563

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsg<tm2.1(PML/RARA)Ley>/Ctsg<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctsg<+>|Ctsg<tm2.1(PML/RARA)Ley>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased acute promyelocytic leukemia incidence
  http://purl.obolibrary.org/obo/MP_0004049

文献

http://purl.org/net/cito/citesAsAuthority

• Geoffrey L. Uy, et.al., A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemia., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20647568