transposition of great arteries_Smo<tm1Amc>/Smo<tm2Amc>,Isl1<tm1(cre)Sev>/Isl1<+>

http://metadb.riken.jp/0004110I129SSv129X1SvJSmotm1AmcSmotm2AmcIsl1tm1creSevIsl1Smotm1AmcSmotm2AmcIsl1tm1creSevIsl1

transposition of great arteries_Smo<tm1Amc>/Smo<tm2Amc>,Isl1<tm1(cre)Sev>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• smoothened, frizzled class receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:108075
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smo<tm1Amc>/Smo<tm2Amc>,Isl1<tm1(cre)Sev>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smo<tm1Amc>|Smo<tm2Amc>|Isl1<tm1(cre)Sev>|Isl1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• transposition of great arteries
  http://purl.obolibrary.org/obo/MP_0004110

文献

http://purl.org/net/cito/citesAsAuthority

• Lizhu. Lin, et.al., Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis., Developmental biology, 2006, 295
  http://rdf.ncbi.nlm.nih.gov/pubmed/16687132