abnormal aortic arch morphology_Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>,Tbx1<tm4(cre/Esr1*)Bld>/Tbx1<+>

http://metadb.riken.jp/0004113I129P2OlaHsd129S7SvEvBrdFgf8tm13MrtFgf8tm14MrtTbx1tm4creEsr1BldTbx1Fgf8tm14MrtFgf8tm13MrtTbx1tm4creEsr1BldTbx1

abnormal aortic arch morphology_Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>,Tbx1<tm4(cre/Esr1*)Bld>/Tbx1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604
• T-box 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98493

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>,Tbx1<tm4(cre/Esr1*)Bld>/Tbx1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgf8<tm1.4Mrt>|Fgf8<tm1.3Mrt>|Tbx1<tm4(cre/Esr1*)Bld>|Tbx1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal aortic arch morphology
  http://purl.obolibrary.org/obo/MP_0004113

文献

http://purl.org/net/cito/citesAsAuthority

• Francesca. Vitelli, et.al., Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants., Developmental biology, 2006, 295
  http://rdf.ncbi.nlm.nih.gov/pubmed/16696966