increased squamous cell carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)105Ayn/0

http://metadb.riken.jp/0004207FVBCgTrp53tm1BrnRb1tm2BrnTgMMTVcre105AynRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgMMTVcre105Ayn0Trp53tm1BrnTgMMTVcre105AynRb1tm2Brn

increased squamous cell carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)105Ayn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 105, Alexander Yu Nikitin
  http://metadb.riken.jp/db/mgi_rdf/MGI:4837142
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)105Ayn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Tg(MMTV-cre)105Ayn|Rb1<tm2Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB.Cg-Trp53<tm1Brn> Rb1<tm2Brn> Tg(MMTV-cre)105Ayn

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased squamous cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004207

文献

http://purl.org/net/cito/citesAsAuthority

• L. Cheng, et.al., Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency., Oncogene, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20676140