increased squamous cell carcinoma incidence_Tg(Mdm2)1Snj/0,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0004207I129S7SvEvBrdC57BL6TgMdm21Snj0Trp53tm1BrdTrp53tm1BrdTrp53tm1BrdTgMdm21Snj

increased squamous cell carcinoma incidence_Tg(Mdm2)1Snj/0,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 1, Stephen N Jones
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388147

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Mdm2)1Snj/0,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Tg(Mdm2)1Snj

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased squamous cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004207

文献

http://purl.org/net/cito/citesAsAuthority

• S N. Jones, et.al., Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis., Proceedings of the National Academy of Sciences of the United States of America, 1998, 95
  http://rdf.ncbi.nlm.nih.gov/pubmed/9861017