increased basal cell carcinoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Krt1-5-cre/ERT)1Ipc/0

http://metadb.riken.jp/0004208I129X1SvJC57BL6SJLGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgKrt15creERT1Ipc0TgKrt15creERT1IpcGtROSA26Sortm1SmoEYFPAmc

increased basal cell carcinoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Krt1-5-cre/ERT)1Ipc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, I Pierre Chambon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177424
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Krt1-5-cre/ERT)1Ipc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Krt1-5-cre/ERT)1Ipc|Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased basal cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004208

文献

http://purl.org/net/cito/citesAsAuthority

• Frauke. Nitzki, et.al., Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20233865