cerebral amyloid angiopathy_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>,Tg(APPSWE)2576Kha/?

http://metadb.riken.jp/0004254I129P2OlaHsdC57BL6SJLApoetm3APOE4MaeApoetm3APOE4MaeTgAPPSWE2576KhaTgAPPSWE2576KhaApoetm3APOE4Mae

cerebral amyloid angiopathy_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>,Tg(APPSWE)2576Kha/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057
• transgene insertion 2576, Karen Hsiao Ashe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385632

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>,Tg(APPSWE)2576Kha/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APPSWE)2576Kha|Apoe<tm3(APOE*4)Mae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cerebral amyloid angiopathy
  http://purl.obolibrary.org/obo/MP_0004254

文献

http://purl.org/net/cito/citesAsAuthority

• John D. Fryer, et.al., Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15772340