cerebral amyloid angiopathy_Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-BACE1)16Vln/0

http://metadb.riken.jp/0004254IC57BL6DBAFVBNTgThy1APPLon2Vln0TgThy1BACE116Vln0TgThy1APPLon2VlnTgThy1BACE116Vln

cerebral amyloid angiopathy_Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-BACE1)16Vln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 16, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3722131
• transgene insertion 2, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-BACE1)16Vln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-APPLon)2Vln|Tg(Thy1-BACE1)16Vln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cerebral amyloid angiopathy
  http://purl.obolibrary.org/obo/MP_0004254

文献

http://purl.org/net/cito/citesAsAuthority

• Michael. Willem, et.al., beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice., The American journal of pathology, 2004, 165
  http://rdf.ncbi.nlm.nih.gov/pubmed/15509532