cerebral amyloid angiopathy_Abca1<tm1Jdm>/Abca1<tm1Jdm>,Tg(Thy1-APP)3Somm/0

http://metadb.riken.jp/0004254IC57BL6JDBA1LacJDBA2Abca1tm1JdmAbca1tm1JdmTgThy1APP3Somm0TgThy1APP3SommAbca1tm1Jdm

cerebral amyloid angiopathy_Abca1<tm1Jdm>/Abca1<tm1Jdm>,Tg(Thy1-APP)3Somm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, Bernd Sommer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448181
• ATP-binding cassette, sub-family A (ABC1), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99607

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abca1<tm1Jdm>/Abca1<tm1Jdm>,Tg(Thy1-APP)3Somm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-APP)3Somm|Abca1<tm1Jdm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * DBA/1LacJ * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cerebral amyloid angiopathy
  http://purl.obolibrary.org/obo/MP_0004254

文献

http://purl.org/net/cito/citesAsAuthority

• Radosveta. Koldamova, et.al., Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice., The Journal of biological chemistry, 2005, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/16207713