cerebral amyloid angiopathy_Tg(Thy1-AppDutch)#Jckr/0,Tg(Thy1-BACE1)54/4Ppa/0

http://metadb.riken.jp/0004254IC57BL6TgThy1AppDutchJckr0TgThy1BACE1544Ppa0TgThy1AppDutchJckrTgThy1BACE1544Ppa

cerebral amyloid angiopathy_Tg(Thy1-AppDutch)#Jckr/0,Tg(Thy1-BACE1)54/4Ppa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 54/4, Paolo Paganetti
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819390
• transgene insertion, Mathias Jucker
  http://metadb.riken.jp/db/mgi_rdf/MGI:4438880

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Thy1-AppDutch)#Jckr/0,Tg(Thy1-BACE1)54/4Ppa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-AppDutch)#Jckr|Tg(Thy1-BACE1)54/4Ppa

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cerebral amyloid angiopathy
  http://purl.obolibrary.org/obo/MP_0004254

文献

http://purl.org/net/cito/citesAsAuthority

• Martin C. Herzig, et.al., BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice., Neuro-degenerative diseases, 2007, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/17596707