abnormal CD8-positive, alpha-beta T cell physiology_Notch2<tm1Hhi>/Notch2<tm1Hhi>,Tg(Cd8a-cre)1Itan/0

http://metadb.riken.jp/0004392IC57BL6CBANotch2tm1HhiNotch2tm1HhiTgCd8acre1Itan0TgCd8acre1ItanNotch2tm1Hhi

abnormal CD8-positive, alpha-beta T cell physiology_Notch2<tm1Hhi>/Notch2<tm1Hhi>,Tg(Cd8a-cre)1Itan/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Ichiro Taniuchi
  http://metadb.riken.jp/db/mgi_rdf/MGI:3851192
• notch 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97364

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Notch2<tm1Hhi>/Notch2<tm1Hhi>,Tg(Cd8a-cre)1Itan/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd8a-cre)1Itan|Notch2<tm1Hhi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal CD8-positive, alpha-beta T cell physiology
  http://purl.obolibrary.org/obo/MP_0004392

文献

http://purl.org/net/cito/citesAsAuthority

• Yoichi. Maekawa, et.al., Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18724371