decreased cochlear outer hair cell number_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>

http://metadb.riken.jp/0004402I129P2OlaHsd129X1SvJC57BL6CD1Cdkn2dtm1MaroCdkn2dtm1MaroCdkn2dtm1Maro

decreased cochlear outer hair cell number_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2d<tm1Maro>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cochlear outer hair cell number
  http://purl.obolibrary.org/obo/MP_0004402

文献

http://purl.org/net/cito/citesAsAuthority

• Heidi. Laine, et.al., p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17287518