small nasal bone_Dph1<tm1.1Cmch>/Dph1<tm1.1Cmch>,Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0004470I129S1Sv129X1SvJC57BL6JCBAJDph1tm11CmchDph1tm11CmchGtROSA26Sortm4ACTBtdTomatoEGFPLuoGtROSA26SorTgWnt1cre11Rth0GtROSA26SorDph1tm11CmchTgWnt1cre11RthGtROSA26Sortm4ACTBtdTomatoEGFPLuo

small nasal bone_Dph1<tm1.1Cmch>/Dph1<tm1.1Cmch>,Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• diphthamide biosynthesis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151233
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dph1<tm1.1Cmch>/Dph1<tm1.1Cmch>,Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Dph1<tm1.1Cmch>|Tg(Wnt1-cre)11Rth|Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• small nasal bone
  http://purl.obolibrary.org/obo/MP_0004470

文献

http://purl.org/net/cito/citesAsAuthority

• Yi-Ru. Yu, et.al., Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome., Human molecular genetics, 2014, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/24895408