decreased response of heart to induced stress_Edn1<tm1Ywa>/Edn1<tm1Ywa>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0004486I129S6SvEvTacFVBNEdn1tm1YwaEdn1tm1YwaTgMyh6cre2182Mds0Edn1tm1YwaTgMyh6cre2182Mds

decreased response of heart to induced stress_Edn1<tm1Ywa>/Edn1<tm1Ywa>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• endothelin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95283

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Edn1<tm1Ywa>/Edn1<tm1Ywa>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Edn1<tm1Ywa>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased response of heart to induced stress
  http://purl.obolibrary.org/obo/MP_0004486

文献

http://purl.org/net/cito/citesAsAuthority

• Ralph V. Shohet, et.al., Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/14764893
• Huan. Huang, et.al., Role of cardiac myocyte-derived endothelin-1 in chagasic cardiomyopathy: molecular genetic evidence., Clinical science (London, England : 1979), 2002, 103 Suppl 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/12193100