decreased response of heart to induced stress_Rassf1<tm1.1Brd>/Rassf1<tm1.1Brd>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0004486I129S7SvEvBrdFVBNRassf1tm11BrdRassf1tm11BrdTgMyh6cre2182Mds0Rassf1tm11BrdTgMyh6cre2182Mds

decreased response of heart to induced stress_Rassf1<tm1.1Brd>/Rassf1<tm1.1Brd>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• Ras association (RalGDS/AF-6) domain family member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928386

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rassf1<tm1.1Brd>/Rassf1<tm1.1Brd>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rassf1<tm1.1Brd>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased response of heart to induced stress
  http://purl.obolibrary.org/obo/MP_0004486

文献

http://purl.org/net/cito/citesAsAuthority

• Dominic P. Del Re, et.al., Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890045