increased incidence of tumors by chemical induction_Tg(Hba-x-v-Ha-ras)TG.ACLed/0,Wrn<tm1Led>/Wrn<tm1Led>

http://metadb.riken.jp/0004499I129FVBNBlackSwissTgHbaxvHarasTGACLed0Wrntm1LedWrntm1LedTgHbaxvHarasTGACLedWrntm1Led

increased incidence of tumors by chemical induction_Tg(Hba-x-v-Ha-ras)TG.ACLed/0,Wrn<tm1Led>/Wrn<tm1Led>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion TG.AC, Philip Leder
  http://metadb.riken.jp/db/mgi_rdf/MGI:2651802
• Werner syndrome RecQ like helicase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109635

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Hba-x-v-Ha-ras)TG.ACLed/0,Wrn<tm1Led>/Wrn<tm1Led>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Hba-x-v-Ha-ras)TG.ACLed|Wrn<tm1Led>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * FVB/N * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of tumors by chemical induction
  http://purl.obolibrary.org/obo/MP_0004499

文献

http://purl.org/net/cito/citesAsAuthority

• Aya. Leder, et.al., Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis., Oncogene, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/12242664