increased incidence of tumors by chemical induction_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>

http://metadb.riken.jp/0004499I129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpCdkn2atm21Rdp

increased incidence of tumors by chemical induction_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm2.1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of tumors by chemical induction
  http://purl.obolibrary.org/obo/MP_0004499

文献

http://purl.org/net/cito/citesAsAuthority

• N E. Sharpless, et.al., Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis., Nature, 2001, 413
  http://rdf.ncbi.nlm.nih.gov/pubmed/11544531
• Norman E. Sharpless, et.al., The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis., Oncogene, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/14724566