increased incidence of tumors by chemical induction_Braf<tm1Cpri>/Braf<tm1Cpri>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-cre/ERT2)1Lru/0

http://metadb.riken.jp/0004499I129Sv129P2OlaHsdC57BL6DBA2SJLBraftm1CpriBraftm1CpriCdkn2atm1RdpCdkn2atm1RdpTgTyrcreERT21Lru0Braftm1CpriCdkn2atm1RdpTgTyrcreERT21Lru

increased incidence of tumors by chemical induction_Braf<tm1Cpri>/Braf<tm1Cpri>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-cre/ERT2)1Lru/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Lionel Larue
  http://metadb.riken.jp/db/mgi_rdf/MGI:3617508
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Cpri>/Braf<tm1Cpri>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-cre/ERT2)1Lru/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Braf<tm1Cpri>|Cdkn2a<tm1Rdp>|Tg(Tyr-cre/ERT2)1Lru

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * DBA/2 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of tumors by chemical induction
  http://purl.obolibrary.org/obo/MP_0004499

文献

http://purl.org/net/cito/citesAsAuthority

• Nathalie. Dhomen, et.al., Oncogenic Braf induces melanocyte senescence and melanoma in mice., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19345328