increased incidence of tumors by UV-induction_Ercc1<tm1Dwm>/Ercc1<tm2Dwm>,Hr<hr>/Hr<hr>,Tg(KRT5-cre)5132Jlj/0

http://metadb.riken.jp/0004501I129P2OlaHsdC57BL6JDBA2JMF1Ercc1tm1DwmErcc1tm2DwmHrhrHrhrTgKRT5cre5132Jlj0TgKRT5cre5132JljErcc1tm1DwmHrhrErcc1tm2Dwm

increased incidence of tumors by UV-induction_Ercc1<tm1Dwm>/Ercc1<tm2Dwm>,Hr<hr>/Hr<hr>,Tg(KRT5-cre)5132Jlj/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• excision repair cross-complementing rodent repair deficiency, complementation group 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95412
• transgene insertion 5132, Jose Luis Jorcano
  http://metadb.riken.jp/db/mgi_rdf/MGI:3050066
• hairless
  http://metadb.riken.jp/db/mgi_rdf/MGI:96223

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ercc1<tm1Dwm>/Ercc1<tm2Dwm>,Hr<hr>/Hr<hr>,Tg(KRT5-cre)5132Jlj/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT5-cre)5132Jlj|Ercc1<tm1Dwm>|Hr<hr>|Ercc1<tm2Dwm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of tumors by UV-induction
  http://purl.obolibrary.org/obo/MP_0004501

文献

http://purl.org/net/cito/citesAsAuthority

• J. Doig, et.al., Mice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progression., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16682947