increased incidence of tumors by UV-induction_Cdkn2a<tm1Rdp>/Cdkn2a<+>,X/Tg(Tyr-HRAS)60Lc

http://metadb.riken.jp/0004501I129SvC57BL6JCBAJFVBNSJLCdkn2atm1RdpCdkn2aXTgTyrHRAS60LcCdkn2aCdkn2atm1RdpTgTyrHRAS60Lc

increased incidence of tumors by UV-induction_Cdkn2a<tm1Rdp>/Cdkn2a<+>,X/Tg(Tyr-HRAS)60Lc

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 60, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:2675988

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<+>,X/Tg(Tyr-HRAS)60Lc

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<+>|Cdkn2a<tm1Rdp>|Tg(Tyr-HRAS)60Lc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of tumors by UV-induction
  http://purl.obolibrary.org/obo/MP_0004501

文献

http://purl.org/net/cito/citesAsAuthority

• John R. Latendresse, et.al., Two cases of uveal amelanotic melanoma in transgenic Tyr-HRAS+ Ink4a/Arf heterozygous mice., Toxicologic pathology, 2007, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/17987514