decreased renal glomerulus number_Bcl2<tm1Dlo>/Bcl2<tm1Dlo>

http://metadb.riken.jp/0004505I129P2OlaHsdC57BL6Bcl2tm1DloBcl2tm1DloBcl2tm1Dlo

decreased renal glomerulus number_Bcl2<tm1Dlo>/Bcl2<tm1Dlo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• B cell leukemia/lymphoma 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:88138

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl2<tm1Dlo>/Bcl2<tm1Dlo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bcl2<tm1Dlo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased renal glomerulus number
  http://purl.obolibrary.org/obo/MP_0004505

文献

http://purl.org/net/cito/citesAsAuthority

• M. Nagata, et.al., Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice., The American journal of pathology, 1996, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/8623928
• N. Gassler, et.al., Oligonephronia, not exuberant apoptosis, accounts for the development of glomerulosclerosis in the bcl-2 knockout mouse., Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/9794553
• K. Nakayama, et.al., Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/8170972