abnormal inner hair cell synaptic ribbon morphology_Bhlhe22<tm3.1(cre)Meg>/Bhlhe22<+>,Gata3<tm1Jfz>/Gata3<tm2Gsv>,Gt(ROSA)26Sor<tm1(CAG-Mafb,-tdTomato)Good>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0004562I129S1Sv129S4SvJae129X1SvJBhlhe22tm31creMegBhlhe22Gata3tm1JfzGata3tm2GsvGtROSA26Sortm1CAGMafbtdTomatoGoodGtROSA26SorGata3tm2GsvBhlhe22tm31creMegBhlhe22GtROSA26SorGtROSA26Sortm1CAGMafbtdTomatoGoodGata3tm1Jfz

abnormal inner hair cell synaptic ribbon morphology_Bhlhe22<tm3.1(cre)Meg>/Bhlhe22<+>,Gata3<tm1Jfz>/Gata3<tm2Gsv>,Gt(ROSA)26Sor<tm1(CAG-Mafb,-tdTomato)Good>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• basic helix-loop-helix family, member e22
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930001
• GATA binding protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95663
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bhlhe22<tm3.1(cre)Meg>/Bhlhe22<+>,Gata3<tm1Jfz>/Gata3<tm2Gsv>,Gt(ROSA)26Sor<tm1(CAG-Mafb,-tdTomato)Good>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gata3<tm2Gsv>|Bhlhe22<tm3.1(cre)Meg>|Bhlhe22<+>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(CAG-Mafb,-tdTomato)Good>|Gata3<tm1Jfz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal inner hair cell synaptic ribbon morphology
  http://purl.obolibrary.org/obo/MP_0004562

文献

http://purl.org/net/cito/citesAsAuthority

• Wei-Ming. Yu, et.al., A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing., eLife, 2013, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/24327562