myocardial fiber degeneration_Irak1<tm1Jth>/Y,Tg(Myh6-Tnf)1Brgi/?

http://metadb.riken.jp/0004566I129SvC57BL6JSJLIrak1tm1JthYTgMyh6Tnf1BrgiIrak1tm1JthTgMyh6Tnf1Brgi

myocardial fiber degeneration_Irak1<tm1Jth>/Y,Tg(Myh6-Tnf)1Brgi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin-1 receptor-associated kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107420
• transgene insertion 1, Brett Giroir
  http://metadb.riken.jp/db/mgi_rdf/MGI:3586561

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irak1<tm1Jth>/Y,Tg(Myh6-Tnf)1Brgi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irak1<tm1Jth>|Tg(Myh6-Tnf)1Brgi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• myocardial fiber degeneration
  http://purl.obolibrary.org/obo/MP_0004566

文献

http://purl.org/net/cito/citesAsAuthority

• James A. Thomas, et.al., IRAK1 deletion disrupts cardiac Toll/IL-1 signaling and protects against contractile dysfunction., American journal of physiology. Heart and circulatory physiology, 2003, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/12860565